Multipotent Mesenchymal Stem Cell-Based Therapies for Spinal Cord Injury: Current Progress and Future Prospects

Mesenchymal stem cells (MSCs) are a promising option for developing new treatments for spinal cord injury (SCI). They can help repair damaged tissue, making them an exciting area of research in regenerative medicine. It is important to study the safety, effectiveness, and best ways to use MSC-based therapies while addressing challenges in bringing these treatments to the clinic. By increasing our knowledge of MSCs and their potential, we can offer hope for better recovery and quality of life for those affected by SCI.

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  MSCs secrete a variety of growth factors and cytokines that exhibit neuroprotective effects, playing a pivotal role in supporting the recovery of damaged neurons after SCI.
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  MSCs possess the remarkable ability to differentiate into various neural cell types, including neurons and glial cells, such as astrocytes and oligodendrocytes
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  MSCs play a critical role in promoting the formation of new blood vessels by secreting pro-angiogenic factors, such as VEGF, angiopoietin-1, and basic fibroblast growth factor (bFGF)