Graphene-Based Materials Prove to Be a Promising Candidate for Nerve Regeneration Following Peripheral Nerve Injury

Biomedicines, 2022 · DOI: 10.3390/biomedicines10010073 · Published: December 30, 2021

Simple Explanation

Peripheral nerve injury is a common medical condition that greatly affects a patient's quality of life. Graphene-based materials (GBMs) have shown the capability to develop bifunctional scaffolds for promoting nerve regeneration. GBMs have unique features that can fabricate an electroactive conductive surface to direct stem cells and improve neural proliferation and differentiation.

Study Duration

Last six years of research

Participants

Not specified

Evidence Level

Review

Key Findings

1
GBMs can enhance interactions between neurons and support neural tissue regeneration by acting as a bridge between regenerating neurones.
2
GBMs are still new in NTE, and there is a need to explore their full potency in this ﬁeld.
3
Current research supports the use of NGCs to repair large nerve defects, particularly in the PNS.

Research Summary

Graphene and its derivatives are promising candidates in the treatment of nerve injury. Graphene is a single-layer atom, with superior mechanical and chemical properties, which include electrical and thermal conductivity, and strength. There are several products currently under development at research centers as well as in industry for the development of nerve conduit from GBMs with biofunctionalization using stem cells and growth factors.

Practical Implications

Nerve Regeneration

GBMs can be used to create scaffolds that promote nerve regeneration, particularly in peripheral nerve injuries.

Stem Cell Differentiation

GBMs can be used to create electroactive conductive surfaces to direct stem cells and improve neural proliferation and differentiation.

Drug Delivery

GBMs composites have represented an appropriate interaction with DNA and RNA for sensing and drug delivery approaches

Graphene-Based Materials Prove to Be a Promising Candidate for Nerve Regeneration Following Peripheral Nerve Injury

Simple Explanation

Key Findings

Research Summary

Practical Implications

Nerve Regeneration

Stem Cell Differentiation

Drug Delivery

Study Limitations

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Graphene-Based Materials Prove to Be a Promising Candidate for Nerve Regeneration Following Peripheral Nerve Injury

Simple Explanation

Key Findings

Research Summary

Practical Implications

Nerve Regeneration

Stem Cell Differentiation

Drug Delivery

Study Limitations

Your Feedback

Was this summary helpful?